Welcome to 107 Myrtle Island Road a once-in-a-lifetime opportunity to own a serene waterfront estate on Bluffton's treasured Myrtle Island. Completely renovated in 2024 by Bluffton Builders & Kelly Caron Designs, this stunning property offers 102 feet of May River frontage with jaw-dropping views of the famous sandbar, tropical breezes, and an unmatched Lowcountry lifestyle. Set on 1.42 acres with lush landscaping and a gated circular drive, the estate features a home with 5 bedrooms and 4 baths. The inviting open floor plan showcases soaring ceilings, a grand living room with fireplace, a formal dining area, and a chefs kitchen with island, long casual bar, and breakfast nook. The owners suite is a retreat of its own, complete with spa-like bath, and sliding doors opening to patios overlooking the river.  Step outside to your personal resort: pool and surrounded by multiple patios, firepit area, and garden spaces that invite outdoor entertaining. A Porte Cochere, 2-car garage, and additional carport ensure convenience for you and your guests. With smart-home upgrades, tankless water heater, this property blends modern comfort with timeless Lowcountry charm. Experience the rare beauty of Myrtle Island living  where privacy, elegance, and unforgettable May River views converge. This is Bluffton's next best sale, and it wont last.